Diagnosis of immunologically induced thrombocytopenia
MAIPA Monoclonal Antibody-specific Immobilization of Platelet Antigen assay
The MAIPA Assay is a qualitative in vitro diagnostic medical device intended for professional laboratory use for the detection and identification of anti-platelet antibodies in serum and plasma samples and for detecting autoantibodies bound to platelets of the patient.
The assay is based on the MAIPA (Monoclonal Antibody-specific Immbilization of Platelet Antigen) technique, described by Kiefel et al can be used for screening serum or plasma for antiplatelet antibodies (indirect MAIPA or MAIPAI) and/or for testing for antibodies bound to the patient's platelets (direct MAIPA or MAIPAD). The antibodies present in serum or plasma may be alloantibodies and/or circulating autoantibodies.
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