Product information
UNITEST Heparin Cofactor II
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A chromogenic method for the determination of heparin cofactor II activity in plasma, based on the inhibition of thrombin.
Test principle
HC II + Dermatan sulphate
⟶
[HC II • Dermatan sulphate]
[HC II • Dermatan sulphate] + Thrombin (excess)
⟶
[HC II • Dermatan sulphate • Thrombin] + Thrombin (residual)
Substrate
Thrombin (residual)⟶
Peptide + pNA
Reagents and stability (after opening)
| Reagent | Quantity | Stability / note |
|---|---|---|
| Thrombin (human) | 1 vial | 8 hours at 4°C 6 months at -20°C |
| Dermatan sulphate | 1 vial | 8 hours at 4°C 6 months at -20°C |
| Thrombin-substrate | 1 vial | 6 months at 4°C |
| Buffer-concentrate | 1 vial | see expiry date |
| Standard plasma | 1 vial | 8 hours at 4°C |
| Article number |
|---|
| 0036 |